Jan 21, 2011. Participating in an 8-week mindfulness meditation program appears to make measurable changes in brain regions associated with memory, sense of self, Celebrating the 200th anniversary of its founding in 1811, Massachusetts General Hospital is the original and largest teaching hospital of Harvard. Sara Lazar, a neuroscientist at Massachusetts General Hospital and Harvard Medical School. what the functional significance of these changes is. Studies by other scientists have…